ADB-PINACA ((S)-N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide).
1. A solution of 1-Pentyl-1H-indazole-3-carboxylic Acid (100 g) in DMF (1000 ml) was treated with EDC (1 equiv), BtOH (1.5 equiv), DIPEA (180 g), L-tert-leucinamide (86 g) and stirred for 24 h.
2. The mixture was partitioned between and H2O (2000 ml) and EtOAc (1000 ml), the layers were separated, and the aqueous layer was extracted with EtOAc (2x1000 ml).
3. The combined organic phases were dried (MgSO4), and the solvent was evaporated under reduced pressure.
4. The crude products were purified by recrystallization to get 92 g of a white solid (yield 63%).
Do i just need these iingredients to make me a batch of ADB? im a noob to chemistry and i dont understand the formula but im willing to do whatever it takes to learn. Do you think its possible for a noob to create Synthetic Cannabinoids? What supplies do i need? I dont even know were to get started, or if someone wants to make it for me, i will pay you.
Im willing to pratice this experiment as many times as needed to get it right. i have money to spend on equiptment and raw materials. i made other post last night dont see it not sure if it got erased, if i cant post here please message me MOD.
you can also email me if you want to help me or like i said ill pay someone to make it for me. [email protected]
1. A solution of 1-Pentyl-1H-indazole-3-carboxylic Acid (100 g) in DMF (1000 ml) was treated with EDC (1 equiv), BtOH (1.5 equiv), DIPEA (180 g), L-tert-leucinamide (86 g) and stirred for 24 h.
2. The mixture was partitioned between and H2O (2000 ml) and EtOAc (1000 ml), the layers were separated, and the aqueous layer was extracted with EtOAc (2x1000 ml).
3. The combined organic phases were dried (MgSO4), and the solvent was evaporated under reduced pressure.
4. The crude products were purified by recrystallization to get 92 g of a white solid (yield 63%).
Do i just need these iingredients to make me a batch of ADB? im a noob to chemistry and i dont understand the formula but im willing to do whatever it takes to learn. Do you think its possible for a noob to create Synthetic Cannabinoids? What supplies do i need? I dont even know were to get started, or if someone wants to make it for me, i will pay you.
Im willing to pratice this experiment as many times as needed to get it right. i have money to spend on equiptment and raw materials. i made other post last night dont see it not sure if it got erased, if i cant post here please message me MOD.
you can also email me if you want to help me or like i said ill pay someone to make it for me. [email protected]
