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Is it really as simple as substituting P2NP with MDP2NP from the one-pot synthesis sticky for amphetamine? What other considerations should I have if this does work?
1. you will require MDP2P/ammonia acetate >imine> to produce MDA.
2. if you have NaBH4, no need for CuCl2.
cyanoBorohydride works better in this reaction.
Unfortunately no access to MDP2P (unless I am able to convert the MDP2NP into MDP2P) or cyanoborohydride. I do have access to NaBH4/CuCl2 from other nitrostyrene experiments and MDP2NP.
The method I am referring to in the original post is here: https://bbgate.com/threads/one-pot-amphetamine-synthesis-from-p2np-with-nabh4-cucl2-1kg-scale.70/
I was just curious if MDP2NP can be substituted for P2NP, would the methylenedioxy group survive the reaction and similarly to P2NP and produce MDA?
I'm reading some success reducing MDP2NP to MDA in this thread here: https://www.thevespiary.org/talk/index.php?topic=15090.0
But I was wondering if anyone had done it and had any first hand experience or tips for the synth, if it is possible.
Is it really as simple as substituting P2NP with MDP2NP from the one-pot synthesis sticky for amphetamine? What other considerations should I have if this does work?
Is it really as simple as substituting P2NP with MDP2NP from the one-pot synthesis sticky for amphetamine? What other considerations should I have if this does work?
Yes it works exactly the same. Result is Mda instead of just A. Would suggest distilling off IPA, adding base and extracting with a NP. Then normal work up
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