Mephedrone (4-MMC) synthesis; easy to perform- high yielding

[K-Cyanide]

It's very strange what's going on here. You post a method and instead of a stimulating discussion, the first comment comes from an apparently confused guy who can do everything much better and faster. How he does it ?, he doesn't tell us this retard.

Then the next one shows up and wants to badmouth the method via pseudo-scientific contributions and remote analysis and thereby acquire customers for his synthesis business, shady.

And finally, Prof. Smart-ass, posts some cynical comments and provides exactly 0 constructive suggestions.

We're not in court here, I don't have to prove anything. The purity of the sample from the academic version was carried out in a professional laboratory with NMR spectra, Infrared and UV spectra, electrospray ionisation mass spectra etc.

I'll think twice about posting anything at all, so it's pointless. In the good old hive forum, a completely different style was cultivated. What a pity.

 

[Researcherr]

It's very strange what's going on here. You post a method and instead of a stimulating discussion, the first comment comes from an apparently confused guy who can do everything much better and faster. How he does it ?, he doesn't tell us this retard.

Then the next one shows up and wants to badmouth the method via pseudo-scientific contributions and remote analysis and thereby acquire customers for his synthesis business, shady.

And finally, Prof. Smart-ass, posts some cynical comments and provides exactly 0 constructive suggestions.

We're not in court here, I don't have to prove anything. The purity of the sample from the academic version was carried out in a professional laboratory with NMR spectra, Infrared and UV spectra, electrospray ionisation mass spectra etc.

I'll think twice about posting anything at all, so it's pointless. In the good old hive forum, a completely different style was cultivated. What a pity.

K-CyanideDon't take personally what the people here post, some of them are smart-asses other know what they talk but would rather make money on their synthesis methods and they don't understand what sharing of knowledge means.

Post your reactions and methods, we can all share and learn from it.

 

[cartelloszetas]

Don't take personally what the people here post, some of them are smart-asses other know what they talk but would rather make money on their synthesis methods and they don't understand what sharing of knowledge means.

Post your reactions and methods, we can all share and learn from it.

ResearcherrGo to School and u teach there.or read books

 

[K-Cyanide]

Don't take personally what the people here post, some of them are smart-asses other know what they talk but would rather make money on their synthesis methods and they don't understand what sharing of knowledge means.

Post your reactions and methods, we can all share and learn from it.

Researcherr@Researcherr
thank you for your kind words. You are right, you should just ignore these guys, though on some days not so easy *grin`*.
By the way, look what this joker answered you. There I make a remote diagnosis: mental disorder in an advanced stage. Take care.

 

[w2x3f5]

It's very strange what's going on here. You post a method and instead of a stimulating discussion, the first comment comes from an apparently confused guy who can do everything much better and faster. How he does it ?, he doesn't tell us this retard.

Then the next one shows up and wants to badmouth the method via pseudo-scientific contributions and remote analysis and thereby acquire customers for his synthesis business, shady.

And finally, Prof. Smart-ass, posts some cynical comments and provides exactly 0 constructive suggestions.

We're not in court here, I don't have to prove anything. The purity of the sample from the academic version was carried out in a professional laboratory with NMR spectra, Infrared and UV spectra, electrospray ionisation mass spectra etc.

I'll think twice about posting anything at all, so it's pointless. In the good old hive forum, a completely different style was cultivated. What a pity.

K-CyanideFor the dumb ones, my signature is specifically for the slick asses who write me in private messages with questions about how to make 10 kg at a time, some of them apparently think that I owe them what. My signature means that I'm not going to help fucking factories for free. You need to be able to take criticism to the point, do you think that your work is of value to the community? No, it does not, in neighboring topics and the output gets higher and the purity is clearly, even without analysis, higher. If you think that you have done something unique, then you are mistaken.

 

[cartelloszetas]

For the dumb ones, my signature is specifically for the slick asses who write me in private messages with questions about how to make 10 kg at a time, some of them apparently think that I owe them what. My signature means that I'm not going to help fucking factories for free. You need to be able to take criticism to the point, do you think that your work is of value to the community? No, it does not, in neighboring topics and the output gets higher and the purity is clearly, even without analysis, higher. If you think that you have done something unique, then you are mistaken.

w2x3f5All people Want help free xD free they have on video xD

 

[K-Cyanide]

For the dumb ones, my signature is specifically for the slick asses who write me in private messages with questions about how to make 10 kg at a time, some of them apparently think that I owe them what. My signature means that I'm not going to help fucking factories for free. You need to be able to take criticism to the point, do you think that your work is of value to the community? No, it does not, in neighboring topics and the output gets higher and the purity is clearly, even without analysis, higher. If you think that you have done something unique, then you are mistaken.

w2x3f5@w2x3f5 I would suggest ending the discussion and just let the other forum members decide what is of value to them and what is not.
I think a rivalry about who has the better methods is not in the spirit of the founders of this forum.

 

[w2x3f5]

@w2x3f5 I would suggest ending the discussion and just let the other forum members decide what is of value to them and what is not.
I think a rivalry about who has the better methods is not in the spirit of the founders of this forum.

K-CyanideI told you everything about your method, the yield of the substance and impurities. And you don't need to tell someone if you can't see behind you.

 

[SonicNL]

It's very strange what's going on here. You post a method and instead of a stimulating discussion, the first comment comes from an apparently confused guy who can do everything much better and faster. How he does it ?, he doesn't tell us this retard.

Then the next one shows up and wants to badmouth the method via pseudo-scientific contributions and remote analysis and thereby acquire customers for his synthesis business, shady.

And finally, Prof. Smart-ass, posts some cynical comments and provides exactly 0 constructive suggestions.

We're not in court here, I don't have to prove anything. The purity of the sample from the academic version was carried out in a professional laboratory with NMR spectra, Infrared and UV spectra, electrospray ionisation mass spectra etc.

I'll think twice about posting anything at all, so it's pointless. In the good old hive forum, a completely different style was cultivated. What a pity.

K-CyanideKeep up your posts. Haters gonn hate anyway lol.

 

[cartelloszetas]

​

Introduction:

In the following, forum members will be presented with a synthesis that is very easy to perform, does not take much time, and gives an exceptionally high yield. The method is a result of many years of experience and inputs from various sources that go back to the times of the legendary Hive forum. All of them deserve high recognition and a great tribute is paid to them.​

​

Reaction: ​

View attachment 13954

Reagents:

​

1. 2-bromo-4'-methylpropiophenone (CAS 1451-82-7) 500 g;​

2. Methylamine 40% aq – 750ml;​

3. Hydrochloric acid (HCl 37%) appr. 250 ml;​

4. Distilled water, clean tap water;​

5. Dichloromethane 2,3l;​

6. Tetrahydrofurane, (Aceton);​

​

Procedure:

1.Dichloromethane (DCM) 1.5 l is poured into the reactor/flask and a condenser is attached.​

2. 2-bromo-4'-methylpropiophenone 500 g (CAS 1451-82-7) is added.​

3. The mixture is stirred until complete amount of bromoketone is dissolved.​

4. Methylamine 40% aq, 750ml is added slowly with a drip funnel.​

6. The mixture is stirred for 2 ½ h at 38 °C. .​

​

View attachment 13947

7 After that, the reaction is quenched by adding 7000ml ice cold clean tap water.

8. The mixture is stirred for 1-2 min and the DCM layer is separated off.​

9. The remaining freebase is extracted with 500 ml DCM.​

10. The combined organic layers where washed twice with 300ml water.​

11. The combined washed organic layers were acidified with 2 M hydrochloric acid (37% hydrochloric acid is diluted 1:5 with water) to reach pH5.5-6 with constant stirring.​

​

​

View attachment 13960 ​

​

​

12. The acidic extract was washed with 300 ml DCM and the water evaporated under vacuum (e.g. in a rotovap) until a viscous liquid is formed.​

​

View attachment 13958 ​

13. After that, the mixture is poured into a buchner funnel and carefully filtered. At first only with gravity, then vacuum is applied until an off white solid is obtained.​

​

View attachment 13950

14. The crude mephedrone hydrochloride is rinsed thoroughly with cold THF (acetone if THF is not available)​

​

View attachment 13951

15. The washed product is put into a Pyrex dish, or similar and dried to constant weight. View attachment 13953 ​

​

Yield 310,57g or 79,59% of theory.

K-CyanideShow what crystal u get if u say i made pure mmc

 

[K-Cyanide]

Show what crystal u get if u say i made pure mmc

cartelloszetasUsually i do not recrystallize, not necessary in my opinion. Glittering crystals is kids stuff. But for you my fellow forum member, I will do it with the next batch.

 

[cartelloszetas]

Usually i do not recrystallize, not necessary in my opinion. Glittering crystals is kids stuff. But for you my fellow forum member, I will do it with the next batch.

K-CyanideI need too see it

 

[cartelloszetas]

U say u can use to wash
Tetrahydrofurane, (Aceton)
No only IPA alkohol and ethyl acetate also u can use and is much more to get in much country

 

[K-Cyanide]

U say u can use to wash
Tetrahydrofurane, (Aceton)
No only IPA alkohol and ethyl acetate also u can use and is much more to get in much country

cartelloszetassure, you can use other solvents. From my experience, THF simply has the best cleaning effect, especially better than acetone.

 

[cartelloszetas]

Now your is dirty when u throw acid and aceton my is xD total white milk when dont need wash any time xD

 

[K-Cyanide]

Congrats, so your product looks like this after the reaction time is over and before any washing/cleaning, correct? If so, we all are curious about your mysterious method to obtain a super clean product out of a reaction, which is per se not clean with a couple of side reactions.

 

[cartelloszetas]

Congrats, so your product looks like this after the reaction time is over and before any washing/cleaning, correct? If so, we all are curious about your mysterious method to obtain a super clean product out of a reaction, which is per se not clean with a couple of side reactions.

K-CyanideI dont wash nothing i throw acid and aceton mix and get this all.u need know what u do freebase i made in 30min

 

[K-Cyanide]

I dont wash nothing i throw acid and aceton mix and get this all.u need know what u do freebase i made in 30min

cartelloszetas 30 min. then the solvent can´t be DCM, maybe ethyl acetate? And then u throw in acetone along with 37% HCl ? Am I getting closer ?

 

[cartelloszetas]

30 min. then the solvent can´t be DCM, maybe ethyl acetate? And then u throw in acetone along with 37% HCl ? Am I getting closer ?

K-CyanideNMP yes made u will see it is so easy

 

[K-Cyanide]

NMP yes made u will see it is so easy

cartelloszetascool , will try it , what temperature do you use ?

 

[cartelloszetas]

cool , will try it , what temperature do you use ?

K-CyanideW srakiej huj cię to obchodzi xD

 

[cartelloszetas]

cool , will try it , what temperature do you use ?

K-CyanideJebać was do dupy !!!

 

[ice4mmc]

I dont wash nothing i throw acid and aceton mix and get this all.u need know what u do freebase i made in 30min

cartelloszetasPodaj Wickr.me/singal/tegram Potrszebuje odpowiedzi na pytania, solidnie zapłacę, lub nawiąże współpracę