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Anybody try do this with methylamine 33% in methanol?
Marvin "Popcorn" Sutton
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I found this on a Russian forum, according to them, 100% Bromoketone reacts in 7 hours at 30 degrees Celsius
If I don't have acetone or IPA I can replacement them with other alcohol like methanol or ethanol?
I hear people after amination wash with water later NaOH this is necessery?
I hear people after amination wash with water later NaOH this is necessery?
I can replace acetone or ethyl acetate IPA?
IPA is not suitable for washing dirty powder, only for acidification or recrystallization.
How minimal acetone must be when I give HCl?Is better give little to base or mix HCl with acetone
How long does it take to dissolve 2-Bromo-4'-methylpropiophenone in DCM?
No so long 5min
When working with 2 bromo 4 methylproiophenone you could dissolve 1 : 3 with DCM and start methylamation with 40%, or am I overlooking things here?
Also it also appears to me that the opinions are divided regarding the temperature on which the methylamation takes place. I read that 32-36 C and the solotion is stirred for 2 - 4 hour.
This how must look.
Have good work
Nice clear yellowish solution you have there. At what point of the synthesis is this picture taken?
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