Synthesis of Amphetamine from P2NP via SnCl2 and Zn

[TucoSalamanca.]

How can I tell if it's amphetamines?

 

[GDC]

How can I tell if it's amphetamines?

TucoSalamanca.Drugtest, heat some of it to the desired temperature (it will melt and burn)

 

[GDC]

Thank you for your reply. I know that DCM is dichloromethane. I don't know whether ethyl acetate is a reactant or an extractant. If it is a reactant, it may not be replaceable. If the extraction agent is replaced with petroleum ether or xylene, will it affect the subsequent reaction?

hacke8no, he use it for extraction but ether is compatible with the GAA?
I think problem is that the GAA is the solvent ...
And don*t forget the exothermic reaction with NaOH

 

[GDC]

Thank you for your reply. I know that DCM is dichloromethane. I don't know whether ethyl acetate is a reactant or an extractant. If it is a reactant, it may not be replaceable. If the extraction agent is replaced with petroleum ether or xylene, will it affect the subsequent reaction?

hacke8oh sry you mean my point 5
You can use ether after zinc reaction

 

[hacke8]

oh sry you mean my point 5
You can use ether after zinc reaction

GDCThank you for your answer. This damn translator always makes us wrong. What kind of reagent is GAA? Glacial acetic acid?

 

[G.Patton]

Thank you for your reply. I know that DCM is dichloromethane. I don't know whether ethyl acetate is a reactant or an extractant. If it is a reactant, it may not be replaceable. If the extraction agent is replaced with petroleum ether or xylene, will it affect the subsequent reaction?

hacke8

I don't know whether ethyl acetate is a reactant or an extractant.

Hello, it is said that there is an extraction procedure. EA here is used as extractant (solvent) for extraction of oxime.

 

[G.Patton]

better yield (90%) and a very pure substance (no additional purification required).

yuiopjklHello. How much grams of the target product have you got?

 

[hacke8]

Hello, thread creator, there are a few questions I would like to answer. 1 Is it necessary to evaporate ethyl acetate after using ethyl acetate extraction? 2 Is it okay to use 37% hydrochloric acid without water? 3 What is the PH value after adding sour water? 4 Can small particles of zinc be used without zinc powder?

 

[blockchain]

Can 37% h2so4 Be used as acid?

 

[TucoSalamanca.]

From 7.5 grams of p2np I obtained 4 grams of amphetamine. Is it good?

 

[mithyl2]

From 7.5 grams of p2np I obtained 4 grams of amphetamine. Is it good?

TucoSalamanca.have you tested it with a reagent?

 

[TucoSalamanca.]

have you tested it with a reagent?

mithyl2I don't know what you mean.

 

[mithyl2]

I don't know what you mean.

TucoSalamanca.A good way to test the validity/purity of a compound is to test it with a reagent chemical:

marquis is often one of the ways of testing amphetamine:
look up dancesafe for example, or 'reagent tests'

 

[mithyl2]

I don't know what you mean.

TucoSalamanca.what was the concentration of the acid you used to precipitate the amphetamine at the end?

 

[TucoSalamanca.]

what was the concentration of the acid you used to precipitate the amphetamine at the end?

mithyl2%98

 

[mithyl2]

%98

TucoSalamanca.How do you have such a precise measurement? Did you have it tested with gas chromatography?

 

[GDC]

How do you have such a precise measurement? Did you have it tested with gas chromatography?

mithyl2he mean the sulfuric acid 98%

 

[mithyl2]

he mean the sulfuric acid 98%

GDCok. i was asking about the purity of the amphetamine just before, so perhaps I should have touched on that. @tucosalamanca, have you definitely got pure amphetamine? mine is extremely contaminated as it has been with other methods

 

[TucoSalamanca.]

ok. i was asking about the purity of the amphetamine just before, so perhaps I should have touched on that. @tucosalamanca, have you definitely got pure amphetamine? mine is extremely contaminated as it has been with other methods

mithyl2I have pure amphetamine, my first synthesis was dirty, my second synthesis was pure.

 

[mithyl2]

I have pure amphetamine, my first synthesis was dirty, my second synthesis was pure.

TucoSalamanca.I don't have access to concentrated sulfuric acid where I am. If you have it could you try to precipitate the amphetamine with 85% phosphoric acid and see how pure your end product is?

I have no idea why the synthesis keeps failing for me, but I think the 85% phosphoric acid I'm using is the only thing that remains the same throughout all of my synthesis attempts.

Thank for any help

 

[TucoSalamanca.]

I don't have access to concentrated sulfuric acid where I am. If you have it could you try to precipitate the amphetamine with 85% phosphoric acid and see how pure your end product is?

I have no idea why the synthesis keeps failing for me, but I think the 85% phosphoric acid I'm using is the only thing that remains the same throughout all of my synthesis attempts.

Thank for any help

mithyl2I tested the boiling point, true, but not the purity.

 

[GDC]

From 7.5 grams of p2np I obtained 4 grams of amphetamine. Is it good?

TucoSalamanca.Thats ok. But the thread opener wrote: 90% of 15g are 13,5g

So you need: 6,75g

 

[TucoSalamanca.]

Thats ok. But the thread opener wrote: 90% of 15g are 13,5g

So you need: 6,75g

GDCHoly shit.